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Genetics Part XV : Eliminating Fault !

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18 Sep 2012 09:57 #101950 by ketchim
A public consultation has been launched to discuss the ethics of :

using three people


to create one baby.... :shocked:

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18 Sep 2012 09:58 #101951 by ketchim
The technique could be used to prevent ;

debilitating and fatal "mitochondrial" diseases,

which are passed down only from mother to child... :cool:

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18 Sep 2012 09:58 #101952 by ketchim
Mitochondria are passed on from the mother's egg to the child -

the father does not pass on mitochondria through his sperm.

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18 Sep 2012 09:59 #101953 by ketchim
In the severest cases the cells of the body are starved of energy.

It can lead to muscle weakness, blindness, heart failure :

and in some cases can be fatal. ::redface::

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18 Sep 2012 10:00 #101954 by ketchim
However, the resulting baby would contain genetic information from three people -

two parents and a donor woman. :wink:

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18 Sep 2012 10:01 #101955 by ketchim

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18 Sep 2012 10:02 #101957 by ketchim
1) Two embryos are fertilised with sperm creating an embryo from the intended parents and another from the donors.

2) The pronuclei, which contain genetic information, are removed from both embryos but only the parents' is kept

3) A healthy embryo is created by adding the parents' pronuclei to the donor embryo, which is finally implanted into the womb

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18 Sep 2012 10:03 #101959 by ketchim
Step 1. Eggs from a mother with damaged mitochondria and a donor with healthy mitochondria are collected.

Step 2. The majority of the genetic material is removed from both eggs. :cool:

Step 3. The mother's genetic material is inserted into the donor egg, which can be fertilised by sperm

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18 Sep 2012 10:04 #101960 by ketchim
Voila !!

there you have it Girls :

Making perfect Babbas !!  :kiss:

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18 Sep 2012 11:19 #101993 by ketchim
Imagine IF that had happened say , 50 years ago :

NO health issues !  :cool:

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